Study Locator
Search Criteria: Mental Health and Well-being Studies;
A Machine Learning Model as an Automatic Tool to Record Human Behavior
A machine learning model may automatically record a human's challenging behavior. Research is needed to learn the value of the model. We want to learn three specific things. 1) How well the model can track challenging behavior? 2) Can the model produce new information based on previous training? 3) How accurate and reliable the model can track challenging behavior based on the new information? The information we gain may aid future patients (IRB#: IRB_00157027)
Behavioral micro-feature discovery using artificial intelligence
This study uses artificial intelligence technology to discover facial and vocal micro-features in individuals with and without depression. (IRB#: IRB_00135711)
Brain MRI scan of schizophrenia or schizoaffective patients vs. healthy controls
The purpose of the study is to gain an improved understanding of whether energy production in neurons is impaired or not. Neurons attempt to increase energy production via several mechanisms under hypoxia [low oxygen saturation in the bloodstream]. Energy production is mandatory for the survival and maintenance of ongoing cellular functions such as communications between neurons, the clearance of toxic products from cell, continuation of enzymatic reactions, ion transport in neurons etc. Phosphorus magnetic resonance spectroscopy (P-MRS) is a magnetic resonance imaging method which provides data regarding the concentrations of neuronal metabolites related to energy production. Our primary aim is to compare the concentrations of these substances before and after hypoxia challenge, which will enable us to comment on the dynamic change in energy production in neurons when higher energy is demanded. This study wishes to test this hypothesis in an effort to learn more about this mechanism, to assist the development of novel treatments for schizophrenia. In this study, we will also analyze certain blood molecules (polyamine and glutathione levels) which have been indirectly related to the receptor function and energy production in neurons, respectively. In brief, glutathione is a natural molecule which is used by neurons to neutralize the toxic by-products [reactive oxygen species, ROS] of energy production. The overproduction or impaired neutralization of reactive oxygen species can result in damage to DNA, proteins, lipid molecules in neurons and dampening of neuronal function. Receptors are located on the surface of neurons which mediates the communication between neurons mostly via molecules called neurotransmitters. Each neurotransmitter binds to the specific receptors assigned to certain neurotransmitters. NMDA [N-methyl-D-aspartate] is the receptor of interest in this study since an association between the impairment in NMDA receptor function and schizophrenia has been reported many times. Polyamines (putrescine, agmatine, spermine and spermidine) are molecules which modulates NMDA receptor function in different ways. Agmatine blocks NMDA function while spermine potentiates the function of these receptors. Putrescine and spermidine have no direct effects on NMDA receptors but they are intermediate molecules between agmatine and spermine. We are planning to compare baseline polyamine level in people with schizophrenia or schizoaffective disorder and healthy counterparts. (IRB#: IRB_00138477)
Cannabis (CBD) Effects of Treating People for Chronic Non-Cancer Pain
Cannabis (CBD) is a treatment shown to reduce non-cancer chronic pain. Research is needed to learn more about how CBD impacts brain chemistry. The information learned will help us better understand the effectiveness of CBD for improving the health of people suffering from chronic pain. (IRB#: IRB_00124865)
Chronic Non-Cancer pain MRI research study evaluating the effects of oral cannabis on chronic pain
The purpose of the study is to evaluate the effects of two substances derived from cannabis (THC and CBD) in participants with chronic non-cancer pain compared with a placebo. The study drug will be administered as an extract mixed in chocolate pudding. Participants will be allowed to stay on their current pain treatments for the study but may not add any more medications during the study. Participation in this study will be confidential. This study has been approved by the FDA, DEA, and University of Utah IRB. (IRB#: IRB_00103451)
Computerized Cognitive Remediation for Treatment Resistant Geriatric Depression
COVID-19 Study
The purpose of this study is to test how well depressed older adults are able to complete a computerized program designed to improve certain types of thinking skills (CCR-GD). We are also interested in whether participating in CCR-GD will improve both your thinking and mood. This research is being done because typical antidepressants are not fully effective and/or may be associated with cognitive deficits in many older adults with depression. This leaves them vulnerable to future depressive episodes. The development of new, non-invasive treatments that may help both mood and cognitive symptoms could potentially help older adults with depression. (IRB#: )
Computerized Cognitive Remediation for Treatment Resistant Geriatric Depression
The purpose of this study is to test how well depressed older adults are able to complete a computerized program designed to improve certain types of thinking skills (CCR-GD). We are also interested in whether participating in CCR-GD will improve both your thinking and mood. This research is being done because typical antidepressants are not fully effective and/or may be associated with cognitive deficits in many older adults with depression. This leaves them vulnerable to future depressive episodes. The development of new, non-invasive treatments that may help both mood and cognitive symptoms could potentially help older adults with depression. (IRB#: IRB_00103167)
COVID-19 and Female College Students
COVID-19 Study
COVID 19 drastically changed the lives of all people, including female college students. Researchers want to learn the effect of COVID 19 and better understand what this population needs to succeed during a pandemic. (IRB#: IRB_00147067)
Depression and Motor Function Study
This study will enroll participants with and without depression to study difference in motor functions between these groups, to understand if motor function predicts response to treatment, and to identify the brain regions involved in motor dysfunction in depression. (IRB#: IRB_00139658)
Effect of Transcranial Magnetic Stimulation (TMS) on the Brain with Emotions
Transcranial Magnetic Stimulation (TMS) is a safe way to help a persons brain. Research is needed to understand how the brain works when a person is emotional. The information we learn will help us know the impact repeated TMS over the front of the brain has on a persons emotions. (IRB#: IRB_00109039)
Health and Safety Consequences of Poor Sleep Health
Sleep is a key factor affecting your overall health. We want to investigate if altering your nightly sleep duration impacts your bodys metabolism (how you metabolize food). We will also look at your physical activity, food intake, and cognition during the study. (IRB#: IRB_00133959)
How COVID-19 has Impacted Secondary School Aged Students with Autism
COVID-19 Study
The purpose of this study is to explore the academic, psychological and social experiences of secondary school aged individuals with an autism spectrum disorder during COVID-19. (IRB#: IRB_00135759)
How Meditation Reduces Chronic Low Back Pain and Opioid Use By Changing the Brain
We are comparing two different forms of meditation-based group therapy versus usual care for people taking opioids to alleviate chronic low back pain. In this study, you may be randomly selected to participate in one of two different forms of meditation-based group therapy (8 weekly sessions), or to continue with your usual low back pain care. You will participate in a pain challenge where you have your brain scanned while you practice meditation to reduce discomfort caused by heat delivered by a safe scientific instrument. You will be compensated for your participation. (IRB#: IRB_00133405)
Improving Assessment of Executive Functioning in Hispanic/Latino/a Older Adults
Neuropsychological evaluations are often used to help doctors determine how well an individual can live independently. However, many of the tests neuropsychologists use were developed on non-Hispanic White individuals and are not as accurate in Hispanic/Latino/a individuals. The goal of this study is to determine which measures are best for assessing functioning in Hispanic/Latino/a individuals so that neuropsychologists have a better understanding of how improve the accuracy of their assessments. (IRB#: IRB_00145891)
Improving Congenital Heart Disease Care for Adolescents and Young Adults
Congenital Heart disease (CHD) is one of the most common birth defects with most major effects diagnosed in infancy. Because there is no cure for CHD it is a lifelong chronic illness. Research is needed to understand the needs of people with CHD as they transition from child to adulthood. This information will improve the care and quality of life for people with CHD. (IRB#: IRB_00149991)
Improving Mental Health Therapy Inequities and Disparities
Racism is a fundamental cause of health inequities and disparities that severely impact the health of Americans. Research is needed to better understand mental health therapists anti-racist practices with people who identify their race as white. The information learned will help design more equitable strategies for people receiving mental health therapy. (IRB#: IRB_00149225)
Massage for Generalized Anxiety Disorder (GAD)
Generalized Anxiety Disorder (GAD) is very upsetting and disabling for people. Massage is known to decrease anxiety. Research is needed to study the effects massage has on symptoms of anxiety and the brain. The information we learn will improve our knowledge of massage to provide more options of care for people with GAD. (IRB#: IRB_00153327)
Measuring Peoples Thermal Comfort in Severe Settings Using Virtual Reality (VR)
The thermal environment of working and learning can impact peoples comfort and energy use of buildings. However, people have limited ability to change their thermal environment in severe conditions (e.g., disasters with limited energy supply). Research is needed to understand peoples thermal comfort and reactions in such severe settings. Therefore, an experiment where a person wears a virtual reality (VR) device to get through possible thermally uncomfortable experience in a safe place will be conducted. The information we learn aims to improve the buildings energy efficiency and occupant indoor comfort, especially during disasters. (IRB#: IRB_00154093)
NAP-HC Study
This brain imaging study will enroll healthy participants in order to compare brain function measures to a separate group of individuals with depression. (IRB#: IRB_00138372)
PH94B: A Possible Medication for Social Anxiety Disorder
PH94B is a potential medication for patients with Social Anxiety Disorder. Scientists and doctors do not know the safety and effectiveness of the drug. Research is needed to learn if the medication may be used to improve the health of patients with Social Anxiety Disorder. (IRB#: IRB_00145861)
Prenatal Latina Discrimination
Studies show that pregnant Latina women are 10-20% more likely to have their babies before the due date. A reason for this may be the greater stress caused by racial discrimination. Research is needed to help scientists and doctors learn how to create better health care for pregnant Latinas. Time Commitment: Approx. 3 weeks Location: Home and smartphone Compensation: Up to $60 *Participation is confidential (IRB#: IRB_00141088)
Prevention for People with Type 2 Diabetes
A persons lifestyle shows to help prevent diabetes. A persons health may be influenced by their partner. Research is needed to learn how useful and successful a diabetes prevention program is when educating a patient with type 2 diabetes and their partner. The information we gain may aid future patients. (IRB#: IRB_00143079)
Storing Information for People with Mood Disorders
Mood disorders like major depressive disorder and bipolar disorder can be long-lasting, reoccurring illnesses. Current ways to help many people often have major barriers. We wish to create a place for research to be stored for people with mood disorders. This will help us design and recruit people to participate in current and future studies of mood disorders. (IRB#: IRB_00154013)
Suicidal Thoughts or Behavior During and After Pregnancy
Pregnancy can be a stressful time in a womans life. This may cause women to have thoughts or actions about self-harm or suicide while they are pregnant. Research is needed to learn more about the effects of motherhood on mental health. The information we learn will help us provide better support for all women during and after pregnancy. (IRB#: IRB_00126952)
Suicide prevention study
We are studying how therapy can help 1850-year-olds.Your input will help us understand suicide therapy interventions. The eligibility survey is quick with a confidential online screening meeting scheduled at your convenience. If you complete all the study procedures, you receive a total of $82 in electronic gift cards. (IRB#: IRB_00135355)
University of Utah Long Covid Registry
COVID-19 Study
Researchers at the University of Utah have established a registry to follow individuals who are experiencing prolonged symptoms after COVID-19 infection. We are interested in following people with "Long Covid" using in depth health surveys and optional blood draws to better understand this condition with the goal of ultimately developing clinical management strategies. (IRB#: IRB_00140978)
Using Mindfulness Techniques to Treat Chronic Pain and Reduce Opioid Use
In this study, we will teach participants mindfulness techniques to help them cope with chronic lower back pain. You must be at least 18 years of age with a diagnosis of lower back pain and taking a prescription opioid medication to participate. Those who choose to enroll will participate in 4 weeks of group therapy (30 minutes per week) group sessions led by a masters-level therapist and prescribed daily at-home mindfulness practice. Participants will be evaluated using interviews and surveys before, after, and during the group therapy intervention. (IRB#: IRB_00135443)
Using neuroimaging to predict chronic pain and medication use
Chronic pain impacts one in every five people in the United States. In this study, we are using brain imaging technologies to better understand chronic pain and to help inform future efforts to develop more effective, personalized treatment strategies for people affected by chronic pain. Specifically, we are interested in seeing whether measures of brain activity can predict future pain and pain medication use. For this study, we are recruiting individuals who are willing to be scanned using functional MRI and to fill out monthly surveys over 6 months. (IRB#: IRB_00128585)