Search Criteria: Heart Studies;
A Study to Test a Tool to Help People for Anticoagulant Drug-to-Drug Interactions
(IRB#: IRB_00167936)
This study is to better understand the safety of oral anticoagulants (medicine for people taken by mouth to prevent blood clots) which may increase the risk of bleeding events if taken with other medications. Researchers at the University of Utah have developed an app called DDInteract to use on a technology device like a cell phone that allows doctors and patients to make decisions about drug reactions with oral anticoagulants and other medications. We want to see if using the app helps patients and their doctors learn and reduce the risks of taking anticoagulants with other medications. People in this study will participate in a virtual focus group (a discussion together with several people using technology such as a cell phone or computer). The information we gain will help us learn more about the effects of taking oral anticoagulants with other drugs.
- All genders
- Over 18 years old
- Volunteers with special conditions
- From Home
- Paid
Biomarkers in People with Heart Failure and Open-Heart Surgery
(IRB#: IRB_00173355)
Biomarkers are a way for doctors to track a persons health such as blood levels. This study wants to see how biomarkers change with normal heart function compared to those with heart failure. The study will measure blood levels before and after heart surgery with a bypass machine (a heart-lung machine that takes over the heart and lungs during surgery). The study has two purposes. One, help doctors learn the differences in heart failure patients response to surgery. Two, identify patients who may benefit from a different type of blood pressure medication after surgery. People in the study will complete surveys and other medical tests related to heart function before and after heart surgery.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Unpaid
Building Transition Readiness Skills for Adolescents and Young Adults with Congenital Heart Disease
(IRB#: IRB_00156291)
Congenital heart disease (CHD) is one of the most common birth defects with most major effects diagnosed in infancy. Because there is no cure for CHD it is a lifelong chronic illness. Research is needed to understand the needs of people with CHD as they transition from child to adulthood. This information will improve the care and quality of life for people with CHD.
- All genders
- Over 7 years old
- Volunteers with special conditions
- From Home
- Paid
Circadian Timing and Chronic Disease
(IRB#: IRB_00159535)
Circadian timing is when a person's daily behaviors occur such as eating and sleeping. Circadian timing may affect a persons health and well-being. Research is needed to learn if improving circadian timing impacts body metabolism (how a person processes and uses food). Which may lead to chronic diseases such as diabetes and heart disease. The research we gain may aid future patients.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Cuffless Blood Pressure Study in Patients with Cardiovascular Conditions
(IRB#: IRB_00170063)
This study aims to test bioimpedance technology to measure blood pressure in patients. Normally people measure their blood pressure with an inflatable cuff on their arm. Bioimpedance technology involves placing sensors in the skin for non invasive recordings. People in this study will wear this new device at the Heart Failure Clinic at the University of Utah Medical Center. These will help us get more measurements to see if the technology works. The study session will last about 30 minutes.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Unpaid
Health and Safety Consequences of Poor Sleep Health
(IRB#: IRB_00133959)
Sleep is a key factor affecting your overall health. We want to investigate if altering your nightly sleep duration impacts your bodys metabolism (how you metabolize food). We will also look at your physical activity, food intake, and cognition during the study.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
How does kidney blood flow affect heart failure?
(IRB#: IRB_00154546)
We want to learn how blood flow in the kidneys might affect heart failure. We will test some people with normal heart function and some with stable heart failure. We will also test some people with diabetes. The tests are a blood test, a urine test, an MRI, an echocardiogram, and an ultrasound. We will also collect information about the medications you take and other medical problems you might have.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Improving Congenital Heart Disease Care for Adolescents and Young Adults
(IRB#: IRB_00149991)
Congenital Heart disease (CHD) is one of the most common birth defects with most major effects diagnosed in infancy. Because there is no cure for CHD it is a lifelong chronic illness. Research is needed to understand the needs of people with CHD as they transition from child to adulthood. This information will improve the care and quality of life for people with CHD.
- All genders
- Over 7 years old
- Volunteers with special conditions
- From Home
- Paid
Improving MRI for People with Heart Disease
(IRB#: IRB_00154019)
People with heart disease may need an imagining scan known as an MRI. Research is needed to improve MRI methods used for finding heart problems and better determining what is normal and what is a disease. These include myocardial fibrosis. The thickening of tissue in heart muscles. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Improving your blood pressure through culinary medicine
(IRB#: IRB_00145096)
High blood pressure is a silent disease that can have devastating consequences. Keeping your blood pressure under control will reduce your risk of developing heart disease, strokes, and even dementia. This study is designed to help you accurately detect if you have high blood pressure, and then get you the treatment you need to keep it under control. In the intervention arm, you will get to participate in a series of cooking classes and learn how to cook foods which will improve your blood pressure without the use of medications. We will discuss components of the DASH diet and teach key culinary skills to help you feel confident preparing and eating more healthful food. If you choose to participate, you will be asked to attend all physician visits, nurse visits, and shared medical visits. You will also be asked to track your blood pressure at home and report it every few weeks to few months. You will be asked to get labs, and weight periodically as well to track your health.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Unpaid
Lifestyle Change Among Women at Risk for Heart Disease and Diabetes
(IRB#: IRB_00146361)
More than half of women of childbearing age may be at risk for heart disease and diabetes. Research is needed to know if women who participate in lifestyle change programs have better health in future pregnancies. To do this we first want to learn women's knowledge about their risk of diabetes and heart disease. Second, we want to know what factors women think may help or prevent them from participating in a healthy lifestyle program. The information we gain may aid future women.
- Female Only
- Over 18 years old
- Volunteers with special conditions
- From Home
- Paid
Magnetic Resonance Imaging (MRI) in Atherosclerotic Disease of the Carotid Artery
(IRB#: IRB_00143315)
Atherosclerotic Disease is a buildup of fat, cholesterol, and other substances on artery walls. An MRI is a way to see places that may have buildup. Research is needed to improve the way an MRI automatically and accurately sees inside the artery walls. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
New Magnetic Resonance Imaging (MRI) Software to Improve Diagnosis of People with Neurovascular Diseases.
(IRB#: IRB_00162281)
Magnetic Resonance Imaging (MRI) is a way to form pictures inside of a persons body. A new MRI software has been designed to improve the quality and diagnosis of neurovascular diseases in the brain and surrounding areas. These diseases can cause problems in the muscles and nerves of a persons body. We want to learn if new MRI software creates better pictures to help people with neurovascular diseases. The information we gain may aid future patients.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Nutrition Education for Diabetes during Pregnancy
(IRB#: IRB_00167234)
This study is to better understand the thoughts and feelings of people who are pregnant with diabetes and have been in a nutrition education program. Diabetes during pregnancy known as gestational diabetes (GDM) is a common issue. We want to hear input and ideas for developing a new nutrition education program for people with this issue. People in this study will complete a brief survey and join a focus group to discuss their experiences along with a follow-up one on one conversation about nutrition. The focus group will be video, and audio recorded. The information will then be written word for word with no names identified. What we learn will help us better know how to develop a nutrition education program for people with GDM.
- Female Only
- Over 18 years old
- Volunteers with special conditions
- From Home
- Paid
Patient and Caregiver Perceptions of Family Wellbeing for Vascular Surgery
(IRB#: IRB_00166345)
Vascular surgery may be done to treat a wide range of people with heart and blood flow issues. Many patients with this procedure can be at risk for other health problems and are over the age of 65. The purpose of this study is to learn more about the needs of the family well-being of vascular surgery patients. This will help doctors better understand decision-making for the family's well-being. People in this study will complete a one-time interview and one-time questionnaires. The interview will be conducted over the phone. Participants will be given a total of $100 for completion of the interview and questionnaires at each time point before and after surgery
- All genders
- Over 18 years old
- Volunteers with special conditions
- From Home
- Paid
Patients After a Stroke who Have Weakness in Either Arms or Legs
(IRB#: IRB_00169101)
Paresis can occur after a person has a stroke causing weakness in either the arms or legs. People who have paresis are at risk of having spasticity. This is when the muscles stiffen or tighten without control and can cause pain. The study wants to see what patients 12 months after the first stroke have spasticity. Participants in the study will complete surveys by phone or online (such as using a computer) and attend in-person study visits. If allowed, the study visits may happen at home. The amount of time spent in the study varies and can last up to 18 months after the first stroke. Participants will be paid for being in the study. Medical information will be collected to track the health of participants.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Sleep and Cardiometabolic Disease
(IRB#: IRB_00164764)
Cardiometabolic disease may put a person at risk of diabetes and heart disease. The amount of time a person sleeps is one factor that can cause the risk of these health issues. Research is needed to learn specific ways to improve a person's nightly sleep that may lower disease risk. The research we gain may aid future patients.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Study Cuffless Blood Pressure
(IRB#: IRB_00162369)
This study is developing a new device to measure blood pressure (how the force of blood goes throughout the body). Normally people measure their blood pressure with an inflatable cuff on their arm. The new device is like a wristwatch with a sensor for blood pressure. People in this study will wear the new device while they exercise in a lab at the University of Utah. Other vital signs will be measured such as body temperature and weight and use an ultrasound machine (a way to see the inside of the body). These will help get more measurements to see if the new device works. The study session will last about 90 minutes.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Studying the genetic factors in smoking-induced vascular disease
(IRB#: IRB_00167355)
Our study will determine whether people who have genetic variants in nicotine receptors have a higher risk for smoking-induced vascular disease. Then we will study the mechanisms and identify potential therapy for smokers carrying genetic variants in nicotine receptors. Our study will educate people carrying genetic variants in nicotine receptors to stop smoking and will provide potential treatments against smoking-induced vascular disease for this population.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Testing Nectero EAST in Adults with Small to Mid-Sized Abdominal Aortic Aneurysms
(IRB#: IRB_00170182)
An abdominal aortic aneurysm is an enlarged artery or tube in your belly that carries blood from your heart to the rest of the body. When the abdominal aorta enlarges the wall weakens and stretches, eventually can get big and thin enough to burst open, which can bleed and cause death. Nectro EAST is a treatment designed to slow the growth and prevent the bursting of an abdominal aortic aneurysm and may decrease the need for surgery in the future. People in the study will be required to come in for in-person clinic visits and be followed for 5 years to monitor the growth of the aneurysm. People randomly chosen to be treated with Nectro EAST will undergo a one-time 1-hour surgery. The surgery is performed through the groin and uses a balloon to deliver medication directly to the aneurysm. The balloon is removed after and recovery is very minimal. Being in the study for both groups lasts 5 years and medical tests will be done to track the health of participants.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
Testing the Study Drug TN-201 in Adults with Symptomatic MYBPC3 Mutation-Associated Hypertrophic Cardiomyopathy
(IRB#: IRB_00166206)
Symptomatic MYBPC3 (a gene found in the muscle of the heart) mutation-associated non-obstructive hypertrophic cardiomyopathy is one of the most common inherited cardiac (heart) diseases. This study will test a drug called TN-201 to treat adults with this disease. The study wants to see if the drug will help people with this disease and is safe. The study will have 2 groups of people receiving different doses of the study drug. All participants will receive the study drug. The drug is given as an infusion (liquid drug given under the skin). Being in the study requires meeting in person at a study clinic at different periods of time over 5 years. Participants will receive payment for participation. Medical tests will be done to track the health of participants.
- All genders
- Over 18 years old
- Volunteers with special conditions
- In Person
- Paid
University of Utah Long Covid Registry
(IRB#: IRB_00140978)
Researchers at the University of Utah have established a registry to follow individuals who are experiencing prolonged symptoms after COVID-19 infection. We are interested in following people with "Long Covid" using in depth health surveys and optional blood draws to better understand this condition with the goal of ultimately developing clinical management strategies.
- All genders
- Over 18 years old
- Volunteers with special conditions
- From Home
- Unpaid