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Clinical Study

Migraine Sensory Biomarkers Study

Migraine progression happens when migraines become significantly more severe or frequent. The goal of this research study is to test if sensitivity to ones environment (i.e. light, touch, sound) can predict migraine progression. By testing sensitivity using different sensory measures (such as touch, light, and sound) we hope to understand risk factors that make migraine progress from an episodic, to a chronic (near-daily), problem. The results of this study will then help future efforts to create preventive interventions in people at-risk for developing chronic migraine. Preventive interventions matter because they help avoid medication overuse headache and ultimately lower risk of progression for those with migraine. There are two main tasks of participating in this study: 1) Completing online questionnaires to evaluate headache history and symptom burden (at screening and over the following 12 months) and 2) completing sensory testing (over two visits). There is compensation associated with participation in this study.


For more information contact:

Cecilia Martindale

IRB#: IRB_00135109 | PI: Melissa Cortez | Department: NEUROLOGY | Approval Date: 2021-06-09 06:00:00
Study Categories: Brain Health Studies | Specialties: Neurology

Who can participate?

 Gender: All

 Age: Over 18 years old

 Volunteers: Volunteers with special conditions

 Location: In Person

Inclusion Criteria:

  • At least 18 years old
  • Migraine with or without aura
  • 5-14 headache days per month

Exclusion Criteria:

  • Headache diagnosis other than migraine or episodic tension headache
  • Pregnancy
  • Anesthetic block or other injectable headache treatments performed in the last 3 months
  • Peripheral neuropathy, partial or total visual/hearing loss or ear/eye injury or surgery, or other medical condition that would restrict the ability to assess sensory amplifications

Will I be paid for my time?


Last Updated: 8/23/22