Study Details
Metformin and Muscle Health Recovery
(IRB#: IRB_00175808)
Times of physical inactivity such as illness, recovery from surgery, or injury in older adults may harm muscle health. Research is needed to learn of ways to improve the muscle response to physical activity and recovery. We will determine if metformin, a diabetes drug, improves muscle recovery during physical inactivity. The information we gain may allow us to better design ways to help muscle health when older adults or those who are overweight become physically inactive and have rehabilitation.
- All genders
- Over 18 years old
- Healthy Volunteers
- In Person
- Paid
Who can participate?
Gender: All genders
Age: Over 18 years old
Volunteers: Healthy Volunteers
Location: In Person
Inclusion Criteria
- Age 60 years and older
- Good general medical health
- Can tolerate at total of 4 muscle biopsies spread over as little as a 5 week period
- Attend in person at the University of Utah
- Can tolerate wearing a leg brace for 2 weeks
Exclusion Criteria
- History of heart, kidney, liver disease, or diabetes
- History of stroke with a motor disability such as difficulty moving a part of your body
- history of cancer
- Currently on a weight-loss diet or drug
- Taking metformin
Will I be paid for my time?
Yes
IRB#: IRB_00175808
PI: Micah Drummond
Department: PHYSICAL THERAPY - COH
Approval Date: 2024-03-12 06:00:00
Study Categories: Bone and Muscle Studies
Specialties: Physical Therapy